Alignment-Free Sequence Comparison Based on Next-Generation Sequencing Reads
نویسندگان
چکیده
منابع مشابه
Alignment-Free Sequence Comparison Based on Next Generation Sequencing Reads: Extended Abstract
Next-generation sequencing (NGS) technologies have generated enormous amounts of shotgun read data, and assembly of the reads can be challenging, especially for organisms without template sequences. We study the power of genome comparison based on shotgun read data without assembly using three alignment-free sequence comparison statistics, D(2), D(*)(2) and D(s)(2), both theoretically and by si...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2013
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2012.0228